Escherichia coli 大肠杆菌照片（美国）
Etiology: Escherichia coli is a gram-negative, lactose-fermenting, indole positive rod. Rabbits are known to be affected by non-toxin producing, enteropathogenic E. coli (EPEC). EPEC adhere to the intestinal mucosa through a 2-step process. First, a bacterial pilus first allows attachment of the bacterial cell to the enterocyte. Second, a more intimate attachment through the eae pathogenicity island disrupts the cytoskeleton and destroys microvilli. A secretory diarrhea is induced by an unknown mechanism. Receptors for EPEC attachment to the epithelial cells are not present in newborn rabbits. They first appear at 21 days and reach normal adult levels by 35 days. The stress of weaning and loss of passively acquired maternal antibody contribute to susceptibility at this time.
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美国 大肠杆菌 Escherichia coli 照片
